Calmodulin
This table contains one of the 43 entries for Calmodulin in the UniProt database, as well as the Calmodulin-like proteins that contain EF Hands, and some of the proteins known to bind either Ca2+-Calmodulin or Apocalmodulin. Links are provided to view the original protein entries. The proteins used to construct the signature for IPR002048 are given with links to the relevant databases.
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UniProt
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Protein name |
Organism |
Function |
IPR002048 signatures |
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Calmodulin |
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Calmodulin |
Homo
sapiens |
Multifunctional |
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Calmodulin-like proteins |
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Calcium-regulated photoprotein: aequorin |
Aequorea victoria
Jellyfish |
Bioluminescence
photoprotein |
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Calcium-binding
protein: CABP |
Entamoeba histolytica
|
Transduction of secondary messages |
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Calcineurin B subunit isoform 1 |
Homo sapiens |
Multifunctional |
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Calmodulin-related protein NB-1 (CLP) |
Homo sapiens
|
Signal
transduction |
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Calcium vector
protein: CAVP |
Branchiostoma lanceolatum
Common lancelet |
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Guanylyl cyclase activating protein 3 (GCAP 3) |
Homo sapiens |
Photoreceptor recovery |
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Calcium and integrin-binding protein 1 (Calmyrin; KIP; CIB) |
Homo sapiens |
Cell growth |
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Myosin-2 light chain |
Saccharomyces cerevisiaeBaker's yeast |
MYO2P stabilisation |
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Myosin essential light chain, striated adductor muscle (E-LC) |
Aequipecten irradiansBay scallop |
Calcium regulation in muscle |
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Myosin regulatory light chain, striated adductor muscle (R-LC) |
Aequipecten irradiansBay scallop |
Calcium regulation in muscle |
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Myosin regulatory light chain cdc4 |
Schizosaccharomyces pombeFission yeast |
Cytokinesis |
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Neurocalcin delta |
Homo sapiens
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Regulation of Rhodopsin phosphorylation |
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Neuronal calcium sensor 1
(Frequenin) |
Homo sapiens |
Regulation of GPCR phosphorylation |
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Recoverin |
Homo sapiens |
Photoresponse |
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Sarcoplasmic calcium-binding protein: SCP |
Perinereis
vancaurica tetradentata Sandworm |
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Troponin
C, slow skeletal and cardiac muscles |
Homo sapiens |
Regulation of striated muscle contraction |
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Ca2+-Calmodulin-binding proteins |
Kinases |
Peripheral
plasma membrane protein CASK (EC 2.7.1.-) |
Homo sapiens
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Elongation factor 2 kinase (EC 2.7.1.-) |
Homo sapiens
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Calcium/calmodulin-dependent
protein kinase type I (EC 2.7.1.123) (CaM kinase I) |
Homo sapiens |
Phosphorylates synapsin I |
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Calcium/calmodulin-dependent protein kinase type IV catalytic chain (EC 2.7.1.123) (CaM kinase IV) |
Homo sapiens |
Ser/Thr protein kinase |
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Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.1.123) (CaM kinase II) |
Homo sapiens |
Long-term potentiation and neurotransmitter release |
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Myosin light chain kinase, smooth muscle and non-muscle isozymes (EC 2.7.1.117) |
Homo sapiens |
Smooth muscle contraction |
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Phosphorylase B kinase alpha regulatory chain, skeletal muscle isoform |
Homo sapiens |
Glycogen metabolism |
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Phosphatases |
Calcineurin B subunit isoform 1 |
Homo sapiens |
Multifunctional |
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Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaMKPase) |
Homo sapiens |
Promotes apoptosis |
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Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform (EC 3.1.3.16) (CAM-PRP) |
Homo sapiens
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Calcineurin
activation |
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Second messenger signalling proteins |
Cysteinyl
leukotriene receptor 2 (GPCR) |
Homo sapiens
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Inflammatory
response |
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CYA1_HUMAN
(Q08828)
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Adenylate cyclase, type I (EC 4.6.1.1) |
Homo sapiens |
Regulatory processes in CNS, including long-term memory |
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Nitric-oxide synthase, brain (EC 1.14.13.39) |
Homo sapiens
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Produces
nitric oxide, which may act as a
neurotransmitter |
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Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) |
Homo sapiens
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CNS
function |
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Cytoskeletal and muscle proteins |
Caldesmon |
Homo sapiens
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Actin and
myosin binding |
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Dystrophin |
Homo sapiens
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Anchoring cytoskeleton
to plasma membrane |
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Myristoylated alanine-rich C-kinase substrate (MARCKS) |
Homo sapiens
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Actin
cross-linking |
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Alpha-1-syntrophin |
Homo sapiens
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Organisation
of membrane proteins |
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Spectrin alpha chain, erythrocyte |
Homo sapiens
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Maintenance
of shape and composition of erythrocyte plasma membrane |
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Spectrin alpha
chain, brain |
Homo sapiens
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Cytoskeletal
movement at plasma membrane |
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Apocalmodulin-binding
proteins |
Neuroproteins |
Glutamate
decarboxylase, 67 kDa isoforms (EC 4.1.1.15) |
Homo sapiens
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Catalyzes
production of neurotransmitter GABA |
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Neuromodulin |
Homo sapiens
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Nerve
growth and CaM storage |
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Neurogranin |
Homo sapiens
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Synaptic
development and remodelling |
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Brain-specific polypeptide PEP-19 |
Homo sapiens
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Receptors |
Inositol 1,4,5-triphosphate receptor |
Xenopus laevis
African
clawed frog |
Endoplasmic
reticulum calcium release |
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Cytoskeletal
and muscle proteins |
Ras GTPase-activating-like protein IQGAP1 |
Homo sapiens
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Regulates
the actin cytoskeleton |
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cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.1.37) |
Homo sapiens
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Smooth
muscle relaxation |
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Myosin Ia |
Homo sapiens
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Directing
movement of organelles along actin filaments |
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Myosin Id |
Rattus norvegicus
Rat |
Intracellular
movement |
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Second
messenger signalling proteins |
Nitric oxide
synthase, inducible |
Rattus norvegicus
Rat |
Produces nitric
oxide, which has diverse functions |
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