ATP Synthase
This table contains entries for different ATP synthases from a variety of species in the UniProt database. Links are provided to view the original UniProt protein entries, and their display in InterPro. Further information can be obtained from GOBASE Organelle Genome Database under the ‘Protein’ search, where there is information on each type of subunit for bacterial, chloroplast and mitochondrial ATP synthase listed under ‘Product Name’ in the search.
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SPTR
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Protein name |
Organism |
InterPro Domain Architecture |
InterPro Graphical Match |
Function |
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F‑ATP synthase (mitochondrial) |
F1 catalytic core |
a chain |
ATP synthase alpha chain,
mitochondrial precursor |
Homo sapiens |
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The alpha chain is a regulatory
subunit. |
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b chain |
ATP synthase beta chain,
mitochondrial precursor |
Homo sapiens |
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The beta chain is the catalytic subunit. |
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d chain |
ATP synthase delta chain,
mitochondrial precursor |
Homo sapiens
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e chain |
ATP synthase epsilon chain,
mitochondrial precursor |
Homo sapiens
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This is the smallest of the 5 chains of the enzymatic component
(coupling factor F1) of the mitochondrial ATPase complex. |
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g chain |
ATP synthase gamma chain,
mitochondrial precursor |
Homo sapiens
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The gamma chain may help regulate ATPase activity and the
flow of protons through the F0 complex. |
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F0 proton channel |
A chain |
ATP synthase A chain |
Homo sapiens |
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Key component of the proton channel for translocation of
protons across the membrane. |
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B chain |
ATP synthase B
chain, mitochondrial |
Homo sapiens |
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C chain |
ATP synthase lipid‑binding protein, mitochondrial precursor (subunit C) |
Homo sapiens |
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ATP synthase lipid-binding protein, mitochondrial precursor (subunit C) |
Homo sapiens |
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ATP synthase lipid-binding protein, mitochondrial precursor (subunit C) |
Homo sapiens |
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D chain |
ATP synthase D
chain, mitochondrial |
Homo sapiens |
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No apparent bacterial homolog and its exact function is
unknown. |
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E chain |
ATP
synthase E chain, mitochondrial |
Homo sapiens |
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F chain |
ATP
synthase F chain, mitochondrial |
Homo sapiens |
None |
None |
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G chain |
ATP synthase
G chain, mitochondrial |
Homo sapiens |
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O chain |
ATP
synthase O chain, mitochondrial |
Homo sapiens |
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Part of stalk linking F0 to F1. Either transmits conformational
changes from F0 into F1 or acts in proton conduction. |
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F6 chain |
ATP synthase coupling
factor 6, mitochondrial precursor |
Homo sapiens
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F6 part of stalk that links F0 to F1. Also involved in the
restoration of oligomycin-sensitive ATPase activity to depleted F1-F0
complexes. |
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8 chain |
ATP synthase
protein 8 |
Homo sapiens
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V‑ATP synthase (vacuolar) |
V1 catalytic
core |
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Vacuolar ATP synthase subunit S1 precursor |
Homo sapiens
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Vacuolar ATP
synthase catalytic subunit A, ubiquitous isoform |
Homo sapiens
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Catalytic subunit of the peripheral V1 complex of vacuolar
ATPase |
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Vacuolar ATP synthase catalytic subunit A, osteoclast isoforms |
Homo sapiens
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Catalytic subunit of the peripheral V1 complex of vacuolar
ATPase. |
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Vacuolar ATP synthase subunit B, kidney isoforms |
Homo sapiens
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Non-catalytic subunit of the peripheral V1 complex of
vacuolar ATPase. |
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Vacuolar ATP synthase subunit B, brain isoforms |
Homo sapiens |
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Non-catalytic subunit of the peripheral V1 complex of
vacuolar ATPase. |
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Vacuolar ATP synthase subunit C |
Homo sapiens |
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Subunit of the peripheral V1 complex of vacuolar ATPase.
Subunit C essential for assembly or catalytic function. |
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Vacuolar ATP synthase subunit D |
Homo sapiens |
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Subunit of the peripheral V1 complex of vacuolar ATPase. |
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Vacuolar ATP
synthase subunit E |
Homo sapiens |
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Subunit of the peripheral V1 complex of vacuolar ATPase
essential for assembly or catalytic function. |
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Vacuolar ATP synthase subunit F |
Homo sapiens |
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Subunit of the peripheral V1 complex of vacuolar ATPase
essential for assembly or catalytic function. |
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Vacuolar ATP synthase subunit G 1 |
Homo sapiens |
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Catalytic subunit of the peripheral V1 complex of vacuolar
ATPase. |
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Vacuolar ATP synthase subunit G 2 |
Homo sapiens |
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Catalytic subunit of the peripheral V1 complex of vacuolar
ATPase. |
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Vacuolar ATP synthase subunit G 3 |
Homo sapiens |
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Catalytic subunit of the peripheral V1 complex of vacuolar
ATPase. |
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Vacuolar ATP synthase subunit H |
Homo sapiens |
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Subunit of the peripheral V1 complex of vacuolar ATPase.
Subunit H activate ATPase activity of the enzyme and couple ATPase activity
to proton flow. |
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V0 proton channel |
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Vacuolar ATP synthase 16 kDa proteolipid subunit |
Homo sapiens
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Proton-conducting pore forming subunit of the membrane
integral V0 complex of vacuolar ATPase. |
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Vacuolar ATP synthase 21 kDa proteolipid subunit |
Homo sapiens
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Proton-conducting pore forming subunit of the membrane
integral V0 complex of vacuolar ATPase. |
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Vacuolar ATP synthase subunit d |
Homo sapiens
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Subunit of the integral membrane V0 complex of vacuolar
ATPase. |
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Vacuolar ATP synthase subunit H |
Homo sapiens
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Vacuolar proton
translocating ATPase 116 kDa subunit a isoform 1 |
Homo sapiens
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Required for assembly and activity of V-ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle |
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F‑ATP synthase (chloroplast) |
F1 catalytic core |
a chain |
ATP synthase alpha chain |
Pisum sativumGarden pea |
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The alpha chain is a regulatory subunit. |
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b chain |
ATP synthase beta chain |
Pisum sativumGarden pea |
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The beta chain is the catalytic subunit. |
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d chain |
ATP synthase delta chain, chloroplast precursor |
Pisum sativum
Garden pea |
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Part of stalk linking F0 to F1. Either transmits
conformational changes from F0 into F1 or acts in proton conduction. |
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e chain |
ATP synthase
epsilon chain |
Pisum sativum
Garden pea |
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g chain |
ATP synthase gamma chain, chloroplast precursor |
Pisum sativum
Garden pea |
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The gamma chain is believed to be important in regulating
ATPase activity and the flow of protons through the F0 complex. |
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F0 proton channel |
A chain |
Chloroplast ATP synthase A chain precursor |
Pisum sativum
Garden pea |
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Key component of the proton channel for translocation of
protons across the membrane. |
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B chain |
ATP synthase B chain |
Pisum sativumGarden pea |
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C chain |
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ATP synthase C
chain |
Pisum sativum
Garden pea |
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F‑ATP synthase (bacterial) |
F1 catalytic core |
a chain |
ATP synthase
alpha chain |
Haemophilus influenzae
Proteobacteria |
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The alpha chain is a regulatory subunit. |
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b chain |
ATP synthase
beta chain |
Haemophilus influenzae
Proteobacteria |
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The beta chain is the catalytic subunit. |
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d chain |
ATP synthase delta chain |
Haemophilus influenzae
Proteobacteria |
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Part of stalk linking F0 to F1. Either transmits
conformational changes from F0 into F1 or acts in proton conduction. |
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e chain |
ATP
synthase epsilon chain |
Haemophilus influenzae
Proteobacteria |
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g chain |
ATP
synthase gamma chain |
Haemophilus influenzae
Proteobacteria |
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The gamma chain is believed to be important in regulating
ATPase activity and the flow of protons through the F0 complex. |
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F0 proton channel |
A chain |
ATP
synthase A chain |
Haemophilus influenzae
Proteobacteria |
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Key component of the proton channel for translocation of
protons across the membrane. |
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B chain |
ATP synthase B chain |
Haemophilus influenzae
Proteobacteria |
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C chain |
ATP synthase C
chain |
Haemophilus influenzae
Proteobacteria |
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Flagellar enzyme |
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Flagellum-specific ATP synthase |
Escherichia coli
Enterobacteria |
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Catalytic
subunit of a protein translocase for flagellum-specific export, or for local circuits
at the flagellum. |
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