T Cell Receptors

This table contains entries for T cell Receptors from human and mouse in the UniProt database. Links are provided to view the original UniProt protein entries, and their display in InterPro.

	SPTR	Protein name	Organism	InterPro Domain Architecture	InterPro Graphical Match	Function
T‑cell receptor a chain	TVA1_HUMAN (P04436)	T-cell receptor alpha chain V region HPB-MLT precursor	Homo sapiens			MHC-antigen binding
	TVA2_HUMAN (P04437)	T-cell receptor alpha chain V region CTL-L17 precursor	Homo sapiens			MHC-antigen binding
	TVA3_HUMAN (P01737)	T-cell receptor alpha chain V region PY14 precursor	Homo sapiens			MHC-antigen binding
	TVA1_MOUSE (P01738)	T-cell receptor alpha chain V region PHDS58 precursor	Mus musculus Mouse			MHC-antigen binding
	TVA2_MOUSE (P01739)	T-cell receptor alpha chain V region 2B4 precursor	Mus musculus Mouse			MHC-antigen binding
T‑cell receptor b chain	TVB1_HUMAN (P01733)	T-cell receptor beta chain V region YT35 precursor	Homo sapiens			MHC-antigen binding
	TVB1_MOUSE (P01734)	T-cell receptor beta chain V region 3H.25 precursor	Mus musculus Mouse			MHC-antigen binding
	TVB2_MOUSE (P01735)	T-cell receptor beta chain V region 86T1 precursor	Mus musculus Mouse			MHC-antigen binding
	TVB3_MOUSE (P01736)	T-cell receptor beta chain V region PHDS203 precursor	Mus musculus Mouse			MHC-antigen binding
	TVB4_MOUSE (P04212)	T-cell receptor beta chain V region LB2 precursor	Mus musculus Mouse			MHC-antigen binding
	TVB5_MOUSE (P04213)	T-cell receptor beta chain V region C5 precursor	Mus musculus Mouse			MHC-antigen binding
	TVB6_MOUSE (P04214)	T-cell receptor beta chain V region E1 precursor	Mus musculus Mouse			MHC-antigen binding
	TVB7_MOUSE (P06320)	T-cell receptor beta chain V region CTL-F3 precursor	Mus musculus Mouse			MHC-antigen binding
T‑cell receptor g chain	TVC_HUMAN (P03979)	T-cell receptor gamma chain V region PT-gamma-1/2 precursor	Homo sapiens			Binds free antigen
	TVC1_MOUSE (P01740)	T-cell receptor gamma chain V region V108A precursor	Mus musculus Mouse			Binds free antigen
	TVC2_MOUSE (P03978)	T-cell receptor gamma chain V region V108B precursor	Mus musculus Mouse			Binds free antigen
	TVC3_MOUSE (P06324)	T-cell receptor gamma chain V region DFL12 precursor	Mus musculus Mouse			Binds free antigen
T‑cell receptor d chain	Q6PJ56_HUMAN (Q6PJ56)	Hypothetical protein (predicted T cell receptor delta-chain precursor)	Homo sapiens			Binds free antigen
	Q5R1A3_MOUSE (Q5R1A3)	TRDV4	Mus musculus Mouse			Binds free antigen
CD3 chains	CD3D_HUMAN (P04234)	T-cell surface glycoprotein CD3 delta chain precursor	Homo sapiens			Mediates signal transduction
	CD3E_HUMAN (P07766)	T-cell surface glycoprotein CD3 epsilon chain precursor	Homo sapiens			Mediates signal transduction
	CD3G_HUMAN (P09693)	T- cell surface glycoprotein CD3 gamma chain precursor	Homo sapiens			Mediates signal transduction
	CD3D_MOUSE (P04235)	T-cell surface glycoprotein CD3 delta chain precursor	Mus musculus Mouse			Mediates signal transduction
	CD3E_MOUSE (P22646)	T-cell surface glycoprotein CD3 epsilon chain precursor	Mus musculus Mouse			Mediates signal transduction
	CD3G_MOUSE (P11942)	T-cell surface glycoprotein CD3 gamma chain precursor	Mus musculus Mouse			Mediates signal transduction
	CD3H_MOUSE (P29020)	T-cell surface glycoprotein CD3 eta chain precursor	Mus musculus Mouse			Probable role in assembly and expression of TCR complex, and in signal transduction.
z chains	CD3Z_HUMAN (P20963)	T-cell surface glycoprotein CD3 zeta chain precursor	Homo sapiens			Probable role in assembly and expression of TCR complex, and in signal transduction.
	CD3Z_MOUSE (P24161)	T-cell surface glycoprotein CD3 zeta chain precursor	Mus musculus Mouse			Probable role in assembly and expression of TCR complex, and in signal transduction.
CD4 receptor	CD4_HUMAN (P01730)	T-cell surface glycoprotein CD4 precursor	Homo sapiens			Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
	CD4_MOUSE (P06332)	T-cell surface glycoprotein CD4 precursor	Mus musculus Mouse			Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
CD8 receptor	CD8A_HUMAN (P01732)	T-cell surface glycoprotein CD8 alpha chain precursor	Homo sapiens			Accessory protein for MHC class-I antigen/T-cell receptor interaction. May play a role in process of T-cell mediated killing.
	CD8B_HUMAN (P10966)	T-cell surface glycoprotein CD8 beta chain precursor	Homo sapiens			Accessory protein for MHC class-I antigen/T-cell receptor interaction. May play a role in process of T-cell mediated killing.
	CD8A_MOUSE (P01731)	T-cell surface glycoprotein CD8 alpha chain precursor	Mus musculus Mouse			Accessory protein for MHC class-I antigen/T-cell receptor interaction. May play a role in process of T-cell mediated killing.
	CD8B_MOUSE (P10300)	T-cell surface glycoprotein CD8 beta chain precursor	Mus musculus Mouse			Accessory protein for MHC class-I antigen/T-cell receptor interaction. May play a role in process of T-cell mediated killing.
CD28	CD28_HUMAN (P10747)	T-cell-specific surface glycoprotein CD28 precursor	Homo sapiens			T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
	CD28_MOUSE (P31041)	T-cell-specific surface glycoprotein CD28 precursor	Mus musculus Mouse			T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
Kinases	ZAP70_HUMAN (P43403)	Tyrosine-protein kinase ZAP-70	Homo sapiens			Associates with z chain. Plays a role in lymphocyte activation.
	ZAP70_MOUSE (P43404)	Tyrosine-protein kinase ZAP-70	Mus musculus Mouse			Associates with z chain. Plays a role in lymphocyte activation.
	LCK_HUMAN (P06239)	Proto-oncogene tyrosine-protein kinase LCK	Homo sapiens			Antigen-induced T-cell activation.
	LCK_MOUSE (P06240)	Proto-oncogene tyrosine-protein kinase LCK	Mus musculus Mouse			Antigen-induced T-cell activation.

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