Kinesin

This table contains entries for a few human kinesin-like proteins and kinesin receptors in the UniProt database. Links are provided to view the original UniProt protein entries, and their display in InterPro.

	SPTR	Protein name	Organism	InterPro Domain Architecture	InterPro Graphical Match	Function
Kinesin Heavy Chains (Kinesin I, or conventional kinesin)	KINN_HUMAN (Q12840)	Neuronal kinesin heavy chain (KIF5A)	Homo sapiens			Microtubule-associated transport motor
	KINH_HUMAN (P33176)	Kinesin heavy chain (KIF5B)	Homo sapiens			Microtubule-associated transport motor
	KIF5C_HUMAN (O60282)	Kinesin heavy chain isoforms (KIF5C)	Homo sapiens			Microtubule-associated transport motor
Kinesin Light Chains	KLC1_HUMAN (Q07866)	Kinesin light chain 1	Homo sapiens			May function in coupling of cargo to heavy chain or in the modulation of its ATPase activity
	KLC2_HUMAN (Q9H0B6)	Kinesin light chain 2	Homo sapiens			May function in coupling of cargo to heavy chain or in the modulation of its ATPase activity
	KLC8_HUMAN (Q9NSK0)	Kinesin-like protein 8	Homo sapiens			May function in coupling of cargo to heavy chain or in the modulation of its ATPase activity
	Q7RTP8_HUMAN (Q7RTP8)	Kinesin light chain 1J	Homo sapiens			May function in coupling of cargo to heavy chain or in the modulation of its ATPase activity
Other N-kinesins	KIF1A_HUMAN (Q12756)	Kinesin-like protein KIF1A	Homo sapiens			Microtubule-associated transport motor
	KIF1B_HUMAN (O60333)	Kinesin-like protein KIF1B	Homo sapiens			Motor for anterograde transport of mitochondria.
	KIF1C_HUMAN (O43896)	Kinesin-like protein KIF1C	Homo sapiens			Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum
	KIF3A_HUMAN (Q9Y496)	Kinesin-like protein KIF3A	Homo sapiens			Microtubule-based anterograde translocator for membranous organelles
	KIF3B_HUMAN (O15066)	Kinesin-like protein KIF3B	Homo sapiens			Involved in tethering the chromosomes to the spindle pole and in chromosome movement
	KIF3C_HUMAN (O14782)	Kinesin-like protein KIF3C	Homo sapiens			Microtubule-based anterograde translocator for membranous organelles
	KIF4A_HUMAN (O95239)	Chromosome-associated kinesin KIF4A	Homo sapiens			Microtubule-associated transport motor; May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
	KIF9_HUMAN (Q9HAQ2)	Kinesin-like protein KIF9	Homo sapiens			Microtubule-associated transport motor
	KIF11_HUMAN (P52732)	Kinesin-like protein KIF11	Homo sapiens			Microtubule-associated transport motor
	KIF12_HUMAN (Q96FN5)	Kinesin-like protein KIF12	Homo sapiens			Microtubule-associated transport motor
	KI13A_HUMAN (Q9H1H9)	Kinesin-like protein KIF13A	Homo sapiens			Microtubule-associated transport motor involved in mannnose-6-P receptor transport to plasma membrane
	KIF14_HUMAN (Q15058)	Kinesin-like protein KIF14	Homo sapiens			Microtubule-associated transport motor
	KIF17_HUMAN (Q9P2E2)	Kinesin-like protein KIF17	Homo sapiens			Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules
	KI20A_HUMAN (O95235)	Kinesin family member 20A	Homo sapiens			Motor for retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubles
	KI21A_HUMAN (Q7Z4S6)	Kinesin family member 21A	Homo sapiens			Microtubule-associated transport motor
	KI21B_HUMAN (O75037)	Kinesin family member 21B	Homo sapiens			Microtubule-associated transport motor
	KIF22_HUMAN (Q14807)	Kinesin-like protein KIF22	Homo sapiens			Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis
	KIF23_HUMAN (Q02241)	Kinesin-like protein KIF23	Homo sapiens			Microtubule-associated transport motor; localizes to the interzone of mitotic spindles
	KIF25_HUMAN (Q9UIL4)	Kinesin-like protein KIF25	Homo sapiens			Microtubule-associated transport motor
	CENPE_HUMAN (Q02224)	Centromeric protein E	Homo sapiens			Microtubule-associated transport motor
	O60845_HUMAN (O60845)	Similar to kinesin-like DNA binding protein	Homo sapiens			Microtubule-associated transport motor
	SNX23_HUMAN (Q96L93)	Kinesin-like motor protein C20orf23	Homo sapiens			Molecular motor involved in intracellular trafficking
C-kinesins	KIFC1_HUMAN (Q9BW19)	Kinesin-like protein KIFC1	Homo sapiens			Minus-end-directed motor enzyme.
	KIFC2_HUMAN (Q96AC6)	Kinesin-like protein KIFC2	Homo sapiens			Microtubule-associated transport motor
	KIFC3_HUMAN (Q9BVG8)	Kinesin-like protein KIFC3	Homo sapiens			Microtubule-associated transport motor
M-kinesins	KIF2_HUMAN (O00139)	Kinesin-like protein KIF2	Homo sapiens			Microtubule-associated transport motor
	Q8N4N8_HUMAN (Q8N4N8)	Kinesin‑like protein KIF2B	Homo sapiens			Microtubule-associated transport motor
	KIF2C_HUMAN (Q99661)	Kinesin-like protein KIF2C	Homo sapiens			Present throughout cell cycle; associates with centromeres at early prophase until after telophase
Kinesin Receptors/Adaptors	A4_HUMAN (P05067)	Amyloid beta A4 protein precursor	Homo sapiens			Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1
	KTN1_HUMAN (Q86UP2)	Kinectin	Homo sapiens			Receptor for kinesin; accumulates in integrin-based adhesion complexes
Scaffolding Proteins	JIP1_HUMAN (Q9UQF2)	C-jun-amino-terminal kinase interacting protein 1	Homo sapiens			May function as a regulator of vesicle transport, through interactions with the JNK-signalling components and motor proteins
	JIP2_HUMAN (Q13387)	C-jun-amino-terminal kinase interacting protein 2	Homo sapiens			Binds TPR motif-containing in kinesin light chain; pre-assembled MAPK8IP1 scaffolding complexes are then transported as cargo of kinesin, to the required subcellular location

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