Sm Ribonucleoproteins

This table contains entries for human Sm and Lsm ribonucleoproteins in the UniProt database. Links are provided to view the original UniProt protein entries, and their display in InterPro.

	SPTR	Protein name	Organism	InterPro Domain Architecture	InterPro Graphical Match	Function
Sm ribonucleoproteins	RSMB_HUMAN (P14678)	Small nuclear ribonucleoprotein associated proteins B and B'	Homo sapiens			Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure.
	SMD1_HUMAN (P62314)	Small nuclear ribonucleoprotein Sm D1	Homo sapiens			May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA.
	SMD2_HUMAN (P62316)	Small nuclear ribonucleoprotein Sm D2	Homo sapiens			Required for pre-mRNA splicing. Required for snRNP biogenesis.
	SMD3_HUMAN (P62318)	Small nuclear ribonucleoprotein Sm D3	Homo sapiens			Associated with snRNP U1, U2, U4/U6 and U5.
	RUXE_HUMAN (P62304)	Small nuclear ribonucleoprotein E	Homo sapiens			Associated with snRNP U1, U2, U4/U6 and U5.
	RUXF_HUMAN (P62306)	Small nuclear ribonucleoprotein F	Homo sapiens			Associated with snRNP U1, U2, U4/U6 and U5.
	RUXG_HUMAN (P62308)	Small nuclear ribonucleoprotein G	Homo sapiens			Associated with snRNP U1, U2, U4/U6 and U5.
	RSMN_HUMAN (P63162)	Small nuclear ribonucleoprotein associated protein N	Homo sapiens			May be involved in brain-specific alternative RNA processing events.
Lsm ribonucleoproteins	LSM1_HUMAN (O15116)	U6 snRNA-associated Sm-like protein LSm1	Homo sapiens			Binds specifically to the 3'-terminal U-tract of U6 snRNA.
	LSM2_HUMAN (Q9Y333)	U6 snRNA-associated Sm-like protein LSm2	Homo sapiens			Binds specifically to the 3'-terminal U-tract of U6 snRNA.
	LSM3_HUMAN (P62310)	U6 snRNA-associated Sm-like protein LSm3	Homo sapiens			Binds specifically to the 3'-terminal U-tract of U6 snRNA.
	LSM4_HUMAN (Q9Y4Z0)	U6 snRNA-associated Sm-like protein LSm4	Homo sapiens			Binds specifically to the 3'-terminal U-tract of U6 snRNA.
	LSM5_HUMAN (Q9Y4Y9)	U6 snRNA-associated Sm-like protein LSm5	Homo sapiens			Involved in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.
	LSM6_HUMAN (P62312)	U6 snRNA-associated Sm-like protein LSm6	Homo sapiens			Binds specifically to the 3'-terminal U-tract of U6 snRNA.
	LSM7_HUMAN (Q9UK45)	U6 snRNA-associated Sm-like protein LSm7	Homo sapiens			Binds specifically to the 3'-terminal U-tract of U6 snRNA.
	LSM8_HUMAN (O95777)	U6 snRNA-associated Sm-like protein LSm8	Homo sapiens			Binds specifically to the 3'-terminal U-tract of U6 snRNA.
	LSM10_HUMAN (Q969L4)	U7 snRNA‑associated Sm‑like protein LSm10	Homo sapiens			Binds specifically to U7 snRNA.
	LSM11_HUMAN (P83369)	U7 snRNA-associated Sm-like protein LSm11	Homo sapiens			Binds specifically to U7 snRNA.

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