Importins

This table contains entries for human importins, as well as for human exportins and nucleoporins, found in the UniProt database. Links are provided to view the original UniProtKB protein entries and their display in InterPro.

	UniProt	Protein name	Organism	InterPro Domain Architecture	InterPro Graphical Match	Function
Importins	IMA1_HUMAN (P52294)	Importin alpha‑1 subunit	Homo sapiens			Nuclear protein import.
	IMA2_HUMAN (P52292)	Importin alpha-2 subunit	Homo sapiens			Nuclear protein import.
	IMA3_HUMAN (O00505)	Importin alpha-3 subunit	Homo sapiens			Nuclear protein import.
	IMA4_HUMAN (O00629)	Importin alpha-4 subunit	Homo sapiens			Nuclear protein import.
	IMA5_HUMAN  (O15131)	Importin alpha-5 subunit	Homo sapiens			Nuclear protein import.
	IMA7_HUMAN (O60684)	Importin alpha‑7 subunit	Homo sapiens			Nuclear protein import.
	IMB1_HUMAN  (Q14974)	Importin beta‑1 subunit	Homo sapiens			Nuclear protein import.
	IMB3_HUMAN (O00410)	Importin beta‑3	Homo sapiens			Nuclear protein import.
	IPO4_HUMAN  (Q8TEX9)	Importin‑4	Homo sapiens			Nuclear protein import.
	IPO9_HUMAN  (Q96P70)	Importin‑9	Homo sapiens			Nuclear protein import.
	IPO11_HUMAN  (Q9UI26)	Importin‑11	Homo sapiens			Nuclear protein import.
	IPO13_HUMAN (O94829)	Importin‑13	Homo sapiens			Nuclear protein import.
Exportins	GLE1_HUMAN (Q53GS7)	Nucleoporin GLE1	Homo sapiens			Required for mRNA export.
	NUPL2_HUMAN (O15504)	Nucleoporin-like 2	Homo sapiens			Required for mRNA export.
	NUP50_HUMAN (Q9UKX7)	Nucleoporin 50 kDa	Homo sapiens			Nuclear protein export.
	NU133_HUMAN (Q8WUM0)	Nuclear pore complex protein Nup133 (Nucleoporin Nup133)	Homo sapiens			Involved in mRNA export.
	NU160_HUMAN (Q12769)	Nuclear pore complex protein Nup160 (Nucleoporin Nup160)	Homo sapiens	/		Involved in mRNA export.
Nucleoporins (NPC proteins)	NUP88_HUMAN (Q99567)	Nuclear pore complex protein Nup88 (Nucleoporin Nup88)	Homo sapiens	/		Essential component of nuclear pore complex.
	NUP93_HUMAN (Q8N1F7)	Nuclear pore complex protein Nup93 (Nucloeporin Nup93)	Homo sapiens			Required for correct NPC assembly.
	NUP98_HUMAN (P52948)	Nuclear pore complex protein Nup98-Nup96 precursor (contains both nucleoporins Nup98 and Nup96)	Homo sapiens			Bidirectional transport across NPC
	NUPL1_HUMAN (Q9BVL2)	Nucleoporin p58/p45	Homo sapiens	/		Required for trafficking across membrane
	NUPL_HUMAN (P52594)	Nucleoporin-like protein RIP	Homo sapiens			May have role in RNA trafficking.
	NU205_HUMAN (Q92621)	Nuclear pore complex protein Nup205 (Nucleoporin Nup205)	Homo sapiens	/		Interacts with NUP93 and NUP35/NUP53.
	NU214_HUMAN (P35658)	Nuclear pore complex protein Nup214 (nucleoporin Nup214)	Homo sapiens			Docking site in receptor-mediated import of cargo
	NDC1_HUMAN (Q9BTX1)	Nucleoporin NDC1	Homo sapiens	/		Required for NPC and nuclear envelope assembly.
	NU62L_HUMAN (Q9H1M0)	Nucleoporin-62-like	Homo sapiens			NPC component.
	NUP37_HUMAN (Q8NFH4)	Nucleoporin Nup37	Homo sapiens			May mediate the assembly of subdomains of the NPC.
	NUP43_HUMAN (Q8NFH3)	Nucleoporin Nup43	Homo sapiens			May mediate the assembly of subdomains of the NPC.
	NUP53_HUMAN (Q8NFH5)	Nucleoporin Nup53	Homo sapiens			Component of the nuclear pore complex.
	NUP54_HUMAN (Q7Z3B4)	Nucleoporin p54	Homo sapiens	/		Required for the trafficking across membrane
	NUP62_HUMAN (P37198)	Nuclear pore glycoprotein p62 (62 kDa nucleoporin)	Homo sapiens			C-terminal may be involved in anchoring p62 to NPC.
	NU107_HUMAN (P57740)	Nuclear pore complex protein Nup107 (Nucleoporin Nup107)	Homo sapiens			Required for assembly of peripheral proteins into NPC.
	NU153_HUMAN (P49790)	Nuclear pore complex protein Nup153 (Nucleoporin Nup153)	Homo sapiens			Possible DNA-binding subunit of the NPC
	NU155_HUMAN (O75694)	Nuclear pore complex protein Nup155 (Nucleoporin Nup155)	Homo sapiens			Essential component of NPC.
	SEH1L_HUMAN (Q96EE3)	Nucleoporin SEH1-like	Homo sapiens			NPC component.

Previous: What InterPro Tells Us