Importins

This table contains entries for human importins, as well as for human exportins and nucleoporins, found in the UniProt database.� Links are provided to view the original UniProtKB protein entries and their display in InterPro.�

	UniProt	Protein name	Organism	InterPro Domain Architecture	InterPro Graphical Match	Function
Importins	IMA1_HUMAN (P52294)	Importin alpha‑1 subunit	Homo sapiens			Nuclear protein import.
	IMA2_HUMAN (P52292)	Importin alpha-2 subunit	Homo sapiens			Nuclear protein import.
	IMA3_HUMAN (O00505)	Importin alpha-3 subunit	Homo sapiens			Nuclear protein import.
	IMA4_HUMAN (O00629)	Importin alpha-4 subunit	Homo sapiens			Nuclear protein import.
	IMA5_HUMAN  (O15131)	Importin alpha-5 subunit	Homo sapiens			Nuclear protein import.
	IMA7_HUMAN (O60684)	Importin alpha‑7 subunit	Homo sapiens			Nuclear protein import.
	IMB1_HUMAN  (Q14974)	Importin beta‑1 subunit	Homo sapiens			Nuclear protein import.
	IMB3_HUMAN (O00410)	Importin beta‑3	Homo sapiens			Nuclear protein import.
	IPO4_HUMAN  (Q8TEX9)	Importin‑4	Homo sapiens			Nuclear protein import.
	IPO9_HUMAN  (Q96P70)	Importin‑9	Homo sapiens			Nuclear protein import.
	IPO11_HUMAN  (Q9UI26)	Importin‑11	Homo sapiens			Nuclear protein import.
	IPO13_HUMAN (O94829)	Importin‑13	Homo sapiens			Nuclear protein import.
Exportins	GLE1_HUMAN (Q53GS7)	Nucleoporin GLE1	Homo sapiens			Required for mRNA export.
	NUPL2_HUMAN (O15504)	Nucleoporin-like 2	Homo sapiens			Required for mRNA export.
	NUP50_HUMAN (Q9UKX7)	Nucleoporin 50 kDa	Homo sapiens			Nuclear protein export.
	NU133_HUMAN (Q8WUM0)	Nuclear pore complex protein Nup133 (Nucleoporin Nup133)	Homo sapiens			Involved in mRNA export.
	NU160_HUMAN (Q12769)	Nuclear pore complex protein Nup160 (Nucleoporin Nup160)	Homo sapiens	/		Involved in mRNA export.
Nucleoporins (NPC proteins)	NUP88_HUMAN (Q99567)	Nuclear pore complex protein Nup88 (Nucleoporin Nup88)	Homo sapiens	/		Essential component of nuclear pore complex.
	NUP93_HUMAN (Q8N1F7)	Nuclear pore complex protein Nup93 (Nucloeporin Nup93)	Homo sapiens			Required for correct NPC assembly.
	NUP98_HUMAN (P52948)	Nuclear pore complex protein Nup98-Nup96 precursor (contains both nucleoporins Nup98 and Nup96)	Homo sapiens			Bidirectional transport across NPC
	NUPL1_HUMAN (Q9BVL2)	Nucleoporin p58/p45	Homo sapiens	/		Required for trafficking across membrane
	NUPL_HUMAN (P52594)	Nucleoporin-like protein RIP	Homo sapiens			May have role in RNA trafficking.
	NU205_HUMAN (Q92621)	Nuclear pore complex protein Nup205 (Nucleoporin Nup205)	Homo sapiens	/		Interacts with NUP93 and NUP35/NUP53.
	NU214_HUMAN (P35658)	Nuclear pore complex protein Nup214 (nucleoporin Nup214)	Homo sapiens			Docking site in receptor-mediated import of cargo
	NDC1_HUMAN (Q9BTX1)	Nucleoporin NDC1	Homo sapiens	/		Required for NPC and nuclear envelope assembly.
	NU62L_HUMAN (Q9H1M0)	Nucleoporin-62-like	Homo sapiens			NPC component.
	NUP37_HUMAN (Q8NFH4)	Nucleoporin Nup37	Homo sapiens			May mediate the assembly of subdomains of the NPC.
	NUP43_HUMAN (Q8NFH3)	Nucleoporin Nup43	Homo sapiens			May mediate the assembly of subdomains of the NPC.
	NUP53_HUMAN (Q8NFH5)	Nucleoporin Nup53	Homo sapiens			Component of the nuclear pore complex.
	NUP54_HUMAN (Q7Z3B4)	Nucleoporin p54	Homo sapiens	/		Required for the trafficking across membrane
	NUP62_HUMAN (P37198)	Nuclear pore glycoprotein p62 (62 kDa nucleoporin)	Homo sapiens			C-terminal may be involved in anchoring p62 to NPC.
	NU107_HUMAN (P57740)	Nuclear pore complex protein Nup107 (Nucleoporin Nup107)	Homo sapiens			Required for assembly of peripheral proteins into NPC.
	NU153_HUMAN (P49790)	Nuclear pore complex protein Nup153 (Nucleoporin Nup153)	Homo sapiens			Possible DNA-binding subunit of the NPC
	NU155_HUMAN (O75694)	Nuclear pore complex protein Nup155 (Nucleoporin Nup155)	Homo sapiens			Essential component of NPC.
	SEH1L_HUMAN (Q96EE3)	Nucleoporin SEH1-like	Homo sapiens			NPC component.

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