Previous Interpro Protein Focus Articles

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You can still find previous articles published to the InterPro blog in the “protein focus” category. They are archived and available in PDF format from this article.

Bee afraid, bee very afraid - neonicotinoids and the nAChRs family

September 2013

Bees are disappearing! The crisis is spreading around the world! To protect these important pollinators, the EU has proposed restricting the use of neonicotinoid pesticides. But what are neonicotinoids? And why were they chosen as pesticides in the first place? Let’s find out more in this article.

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Wilson’s disease and the copper ATPase transporters

April 2013

In the American TV series House, episode ‘The Socratic Method’, a mother seeming to suffer from schizophrenia is admitted to hospital. Let’s find out how House solves this case and how we can use InterPro to know more about the Wilson’s disease protein and its homologues.

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November 2012

Protein family classification is often achieved using computerised multiple protein sequence alignment and structural analysis. However, it’s not always straightforward to define a protein family. In this article, we will take a look at an example-the Rad9/Ddc1 family.

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Relax and unwind: the RecQ DNA helicase family

June 2012

When people go on holiday or travel for a conference, fitting all their clothes, books and a laptop into a small suitcase often presents a challenge. For eukaryotic cells, packing their lengthy genomic DNA into their relatively small nucleus presents a similar challenge.

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Killer toxin Protein (KP4): Harnessing the power of a killer toxin for good

September 2011

The yeast killer toxin protein KP4 is currently used in agriculture as a means of protecting plants form fungal infections. There is an ever widening scope of the potential applications of this protein in biotechnology and medicine.

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Chemokine receptor type 4 (CXCR4): diseases, drugs and druggable target molecules

February 2011

Chemokine Receptor type 4 (CXCR4) is of increasing interest as a drug target. This molecule is thought to be involved in many disease states including more than 23 types of cancer and several immunodeficiency disorders.

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Collagen: a ubiquitous, unsung protein

January 2009

Collagen is a long, fibrous structural protein that is usually associated with cosmetic enhancements, movie star’s lips and anti-aging lotions. Just as one hopes for these movie stars; there is much more to collagen than what appears on the surface. Collagen is the most abundant protein in mammals.

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Fatty Acid Synthase

June 2007

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May 2007

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April 2007

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Zinc fingers

March 2007

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RNA exosomes

February 2007

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January 2007

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December 2006

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November 2006

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Cytochrome P450

October 2006

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Elongation Factors

September 2006

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August 2006

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Amyloid-beta Precursor Protein

July 2006

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June 2006

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Glucose Oxidase and Biosensors

May 2006

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Bird Flu Haemagglutinin

April 2006

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Tissue Factor

March 2006

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February 2006

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DNA topoisomerase

January 2006

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ATP Synthase

December 2005

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Acetylcholine Receptors

November 2005

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October 2005

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Cholera Toxin

September 2005

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TRK Receptors

August 2005

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TATA-box Binding Proteins

July 2005

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Carotenoid oxygenase

June 2005

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Sm Ribonucleoproteins

May 2005

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April 2005

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T Cell receptors

March 2005

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Major Histocompatibility Complex (MHC)

February 2005

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Phenylalanine Hydroxylase

January 2005

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December 2004

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Photosystem II

November 2004

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G Proteins

October 2004

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September 2004

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August 2004

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DNA Ligase IV

July 2004

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Snake Venom: Bungarotoxins

June 2004

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Serpins: alpha-1 antitrypsin

May 2004

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Growth Hormone Receptors

April 2004

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Calcium Pumps

March 2004

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Enzymes of Glycolysis

February 2004

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Carbonic Anhydrase

January 2004

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Catabolite Activator Protein

December 2003

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Simian Virus 40

November 2003

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October 2003

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Oestrogen receptors

September 2003

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August 2003

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SRC, proto-oncogene tyrosine-protein kinase

July 2003

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Green fluorescent protein

June 2003

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